The aim of WorkPackage 2 is to identify novel peroxisomal transporters and to analyze their function.
We will use:
- proteomics approaches using purified peroxisomal membrane fractions
- proteomic analyses on affinity-purified complexes of Pex19, the receptor for peroxisomal membrane proteins
- in vivo screens to identify proteins that have the capacity to transport various molecules across peroxisomal membranes
658 total views, 1 views today