A PhD position is available at the Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, The Netherlands.
Project title: Peroxisome-vacuole membrane contact sites (MCS) in yeast
- Comparison of wild-type and peroxisome-deficient yeast cells by metabolomics/lipidomics to identify how peroxisome deficiency affects cell metabolism and signalling networks.
- To identify novel contact site proteins using proteomic approaches and bioinformatics search for homologues
- Validation of selected, putative yeast contact site proteins using advanced microscopy techniques including correlative light and electron microscopy
- Detailed functional analysis of selected novel vacuolar contact site proteins (peroxisome biogenesis, dynamics and metabolism) in mutant strains using biochemical, microscopy and “omics’ approaches.
Location: Groningen, The Netherlands
Supervisor: Prof. Dr. I.J. van der Klei (i.j.van.der.kleiATrug.nl)
Co-supervisors: Prof. Dr. R. Erdmann & Dr. M. Danielsen (MS-Omics ApS)
Planned secondments: Ruhr University Bochum, University of Freiburg, MS-Omics ApS
Required subject specific skills and expertise: a master’s degree in molecular life sciences (molecular cell biology, molecular genetics, biochemistry). Experience in yeast research is advantageous, but not mandatory.
Application deadline: 28/10/2018
Starting date: April 1, 2019
The previous deadline for applications has been extended until October 28.
Please note: Applications that have already been submitted are well received and under consideration. No further action is required on behalf of applicants who applied before the previous deadline
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